Come Visit Us at AACR! Booth #2141.

MERIT40 Antibody

MERIT40 (mediator of RAP80 interactions and targeting subunit of 40 kDa) is a component of the BRCA1-A complex, a complex that specifically recognizes 'Lys-63'-linked ubiquitinated histones H2A and H2AX at DNA lesions sites and leads to targeting of the BRCA1-BARD1 heterodimer to sites of DNA damage at double-strand breaks (DSBs). In the BRCA1-A complex, it is required for the complex integrity and its localization at DSBs. MERIT40 probably also plays a role as a component of the BRISC complex, a multiprotein complex that specifically cleaves 'Lys-63'-linked ubiquitin [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q9NWV8].
BABAM1
BRISC and BRCA1 A complex member 1
BRISC and BRCA1-A complex member 1
:  BRCA1-A complex subunit MERIT40 BRISC and BRCA1-A complex member 1 C19orf62 HSPC142 mediator of Rap80 interactions and targeting 40 kDa mediator of RAP80 interactions and targeting subunit of 40 kDa MERIT40 NBA1 new component of the BRCA1-A complex new component of the BRCAA1 A complex More... Less...
Product
Specifications
Ordering Information
Human
IP
Between 1 and 50
$339
$99
Human
IP, IHC
Between 175 and 225
$339
$99
Human
IP, IHC
Includes: 1 each of A302-515A and A302-516A
$472
Includes: 1 each of A302-515A and A302-516A
Human
IHC
Between 175 and 225
$360
$99