The conjugation of ubiquitin to proteins is an important means to regulate protein activity for many cellular processes by tagging them for degradation. Lasu1/Ureb1 is an E3 ubiquitin protein ligase that mediates the ubiquitination of core histones, Mcl-1, Cdc6, and p53. Lasu1/Ureb1 expression is regulated during spermatogenesis and appears to play a role in chromatin modification in germ cells as well as other tissues.
ARF-binding protein 1•
BJ-HCC-24 tumor antigen•
HECT domain protein LASU1•
HECT, UBA and WWE domain containing 1•
HECT, UBA and WWE domain-containing protein 1•
homologous to E6AP carboxyl terminus homologous protein 9•
large structure of UREB1•
Mcl-1 ubiquitin ligase E3•
upstream regulatory element-binding protein 1•
URE-binding protein 1•More...Less...