ETO (eight twenty-one protein) is also known as MTG8 (myeloid translocation gene on 8q22) and was identified as part of an 8:21 chromosomal breakpoint in leukemia cells. ETO is encoded by the RUNX1T1 (runt-related transcription factor; translocated to, 1 (cyclin D-related) gene and functions as a transcriptional co-repressor.
acute myelogenous leukemia 1 translocation 1, cyclin-D related•
core-binding factor, runt domain, alpha subunit 2; translocated to, 1•
eight twenty one protein•
myeloid translocation gene on 8q22•
runt related transcription factor 1; translocated to, 1 (cyclin D related)•
zinc finger MYND domain-containing protein 2•