CC2D1A functions as a transcriptional repressor of FRE (five repressor element) DNA element. As a repressor of this element, CC2D1A represses serotonin-1A receptor and dopamine-D2 receptor gene expression and has been linked to nonsyndromic mental retardation and psychiatric illnesses. The DNA binding and repressor activities of CC2D1A are regulated by the calcium-calmodulin-dependent protein kinase.
Akt kinase-interacting protein 1•
five prime repressor element under dual repression-binding protein 1•
five repressor element under dual repression-binding protein 1•
FRE under dual repression-binding protein 1•
mental retardation, nonsyndromic, autosomal recessive, 3•
putative NF-kappa-B-activating protein 023N•
putative NFkB activating protein•More...Less...