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CD38 Antibody

CD38 (ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1) is a type II transmembrane glycoprotein that synthesizes and hydrolyzes cyclic adenosine 5'-diphosphate-ribose, an intracellular calcium ion mobilizing messenger. The release of soluble protein and the ability of membrane-bound protein to become internalized indicate both extracellular and intracellular functions for the protein. The functional CD38 molecule is a dimer, with the central portion containing the catalytic site. CD38 is used as a prognostic marker for patients with chronic lymphocytic leukemia. Alternative splicing results in multiple transcript variants. [taken from NCBI Entrez Gene (Gene ID: 952)].
CD38 molecule
ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1
:  2'-phospho-ADP-ribosyl cyclase 2'-phospho-ADP-ribosyl cyclase/2'-phospho-cyclic-ADP-ribose transferase 2'-phospho-cyclic-ADP-ribose transferase ADPRC 1 ADPRC1 ADP-ribosyl cyclase 1 ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 cADPr hydrolase 1 CD antigen CD38 CD38 antigen (p45) cluster of differentiation 38 cyclic ADP-ribose hydrolase 1 ecto-nicotinamide adenine dinucleotide glycohydrolase NAD(+) nucleosidase T10 More... Less...
Ordering Information
residues 43-300 (ECD)