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CSTF2T/TauCSTF64 Antibody

CSTF2T, also known as tauCSTF-64, is a paralog of CstF-64, a component of the cleavage stimulation factor (CstF) that processes 3’-end formation and polyadenylation of mRNAs. The human CSTF2T/TauCSTF64 gene is located at 10q22-23, a site associated with neurological problems and male infertility. CSTF2T is expressed in all tissues and throughout meiosis in male germ cells. CstF-64 is also expressed ubiquitously; however because it is located on the X chromosome, its expression is temporarily silenced in germ cells by meiotic sex chromosome inactivation. During this inactivation, it is hypothesized that CSTF2T/TauCSTF64 can compensate for the loss of CstfF-64 expression. Recently, targeted disruption of CSTF2T/TauCSTF64 in mice has been shown to cause aberrant spermatogenesis and infertility providing more evidence for its importance in spermatogenesis.
CSTF2T
cleavage stimulation factor subunit 2 tau variant
Cleavage stimulation factor subunit 2 tau variant
:  CF-1 64 kDa subunit tau CF-1 64 kDa subunit tau variant cleavage stimulation factor 64 kDa subunit tau Cleavage stimulation factor 64 kDa subunit tau variant cleavage stimulation factor subunit 2 tau variant cleavage stimulation factor subunit 2, tau cleavage stimulation factor, 3' pre-RNA, subunit 2, 64kDa, tau cleavage stimulation factor, 3' pre-RNA, subunit 2, tau CSTF 64 kDa subunit tau CSTF 64 kDa subunit tau variant CstF-64T tauCstF-64 More... Less...
Product
Specifications
Ordering Information
Human
IP
Between 225 and 275
$339
$99
Human
WB, IP, IHC
Between 566 and 616
$339
$229
$99
Human
WB, IP, IHC
Includes: 1 each of A301-486A and A301-487A
$472
Includes: 1 each of A301-486A and A301-487A
Human
IHC
Between 566 and 616
$360
$99