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AKAP8/AKAP95 Antibody

AKAP8/AKAP95 has been characterized as a 95 kDa protein kinase A (PKA)-anchoring protein and regulatory subunit of PKA that functions to recruit the condensin complex for chromosome condensation during mitosis. A role in DNA replication has also been demonstrated through its interaction with the pre-replication complex component, MCM2 (mini-chromosome maintenance 2). Inhibition of AKAP8/AKAP95 association with MCM2 inhibits replication initiation and elongation in vitro. AKAP8/AKAP95 has also been shown to be involved in apoptosis. KAP8/AKAP95 associates with caspase 3 and serves as a carrier to transport caspase 3 from the cytoplasm to the nucleus to induce morphological changes in the nucleus.
AKAP8
A-kinase anchoring protein 8
A-kinase anchor protein 8
:  A kinase (PRKA) anchor protein 8 AKAP 95 AKAP-8 AKAP95 AKAP-95 A-kinase anchor protein 95 kDa A-kinase anchor protein, 95kDa DKFZp586B1222
Product
Specifications
Ordering Information
Human
WB, IP
Between 575 and 625
100
$339
$229
$99
Human, Mouse
WB, IP, IHC-P
Between 642 and C-term
100
$339
$229
$99
Human, Mouse
100
Includes: 1 each of A301-061A and A301-062A
$472
Includes: 1 each of A301-061A and A301-062A
Human, Mouse
IHC-P
Between 642 and C-term
100
$360
$99