cAbl Antibody

c-Abl is the human cellular homolog of a the v-Abl viral oncogene. v-Abl was originally discovered as a mouse cell-derived sequence in the genome of the Abelson murine leukemia virus (A-MuLV), a transforming retrovirus isolated by the laboratory of Dr. H.T. Abelson. c-Abl is a tyrosine kinase from the Src-family of tyrosine kinases that localizes to both the cytoplasm and nucleus. It bears an SH2 (src-homology 2) and SH3 (src-homology 3) domain responsible for mediating c-Abl protein-protein interactions. c-Abl is implicated to play a role in multiple cellular processes such as cell cycle checkpoint signaling, apoptosis, cell differentiation, cell adhesion, and transcriptional regulation. Chromosomal translocations involving the c-Abl gene are associated with human leukemias.
ABL1
ABL proto-oncogene 1, non-receptor tyrosine kinase
Tyrosine-protein kinase ABL1
:  Abelson murine leukemia viral oncogene homolog 1 Abelson tyrosine-protein kinase 1 ABL bcr/abl bcr/c-abl oncogene protein c-ABL c-abl oncogene 1, non-receptor tyrosine kinase c-abl oncogene 1, receptor tyrosine kinase c-ABL1 JTK7 p150 proto-oncogene c-Abl proto-oncogene tyrosine-protein kinase ABL1 v-abl v-abl Abelson murine leukemia viral oncogene homolog 1 More... Less...
Product
Specifications
Ordering Information
Human
WB, IP, IHC, ICC, IF, PLA
Between 550 and 600
$339
$229
$99
Human
IP, IHC, ICC, IF, PLA
Between 850 and 900
$339
$99
Human
WB, IP, IHC, ICC, IF, PLA
Includes: 1 each of A301-660A and A301-661A
$472
Includes: 1 each of A301-660A and A301-661A
Human
IHC, ICC, IF
Between 850 and 900
$360
$99