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VAC14 Antibody

The content of phosphatidylinositol 3,5-bisphosphate (PtdIns(3,5)P2) in endosomal membranes changes dynamically with fission and fusion events that generate or absorb intracellular transport vesicles. VAC14 is a component of a trimolecular complex that tightly regulates the level of PtdIns(3,5)P2. Other components of this complex are the PtdIns(3,5)P2-synthesizing enzyme PIKFYVE (MIM 609414) and the PtdIns(3,5)P2 phosphatase FIG4 (MIM 609390). VAC14 functions as an activator of PIKFYVE (Sbrissa et al., 2007 [PubMed 17556371]) [taken from NCBI Entrez Gene (Gene ID: 55697)].
Vac14, PIKFYVE complex component
Protein VAC14 homolog
:  ArPIKfyve protein VAC14 homolog Tax1 (human T-cell leukemia virus type I) binding protein Tax1-binding protein 2 TAX1BP2 TRX
Ordering Information
Between 732 and 782