PSMC4 Antibody

PSMC4 [proteasome (prosome, macropain) 26S subunit, ATPase, 4] is a member of the triple-A family of ATPases that is a component of the 19S regulatory subunit and plays a role in 26S proteasome assembly. The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. PSMC4 interacts with gankyrin, a liver oncoprotein, and may also play a role in Parkinson's disease through interactions with synphilin-1 [taken from NCBI Entrez Gene (Gene ID: 5704)].
PSMC4
proteasome 26S subunit, ATPase 4
26S protease regulatory subunit 6B
:  26S proteasome AAA-ATPase subunit RPT3 MB67 interacting protein MB67-interacting protein MGC13687 MGC23214 MGC8570 MIP224 protease 26S subunit 6 proteasome (prosome, macropain) 26S subunit, ATPase, 4 Proteasome 26S subunit ATPase 4 RPT3 S6 Tat-binding protein 7 TBP7 TBP-7 More... Less...
Product
Specifications
Ordering Information
Human
WB, IP, IHC
Between 1 and 50
$339
$229
$99
Human
WB, IP, IHC
Between 368 and 418
$339
$229
$99
Human
WB, IP, IHC
Includes: 1 each of A303-849A and A303-850A
$472
Includes: 1 each of A303-849A and A303-850A