The Apoptosis-Stimulating Protein of P53 (ASPP) family of proteins is comprised of ASPP1, ASPP2 and iASPP. ASPP1 and ASPP2 function to direct the cell away from cell cycle arrest and towards death by activating p53 family members, while iASPP functions to inhibit p53 mediated apoptosis. ASPP proteins have been shown to interact with p53, Bcl-2, and ReLA/p65.
apoptosis-stimulating of p53 protein 2•
apoptosis-stimulating protein of p53, 2•
p53-binding protein 2•
renal carcinoma antigen NY-REN-51•
tumor suppressor p53-binding protein 2•