Septin 2 Antibody

Septin 2 is a filament-forming cytoskeletal GTPase. Septin 2 is required for normal organization of the actin cytoskeleton and plays a role in the biogenesis of polarized columnar-shaped epithelium by maintaining polyglutamylated microtubules, thus facilitating efficient vesicle transport, and by impeding MAP4 binding to tubulin. It is required for the progression through mitosis, and it forms a scaffold at the midplane of the mitotic splindle required to maintain CENPE localization at kinetochores and consequently chromosome congression. During anaphase, Septin 2 may be required for chromosome segregation and spindle elongation. Septin 2 also plays a role in ciliogenesis and collective cell movements [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q15019].
SEPT2
septin 2
Septin-2
:  DIFF6 hNedd5 KIAA0158 NEDD5 NEDD-5 neural precursor cell expressed developmentally down-regulated protein 5 neural precursor cell expressed, developmentally down-regulated 5 Pnutl3
Product
Specifications
Ordering Information
Human, Mouse
WB, IP
Between 275 to 325
$339
$229
$99
Human, Mouse
WB, IP
Between 311 to 361
$339
$229
$99
Human, Mouse
WB, IP
Includes: 1 each of A304-210A and A304-211A
$472
Includes: 1 each of A304-210A and A304-211A