TIGIT is a member of the PVR (poliovirus receptor) family of immunoglobin proteins and is expressed on several classes of T cells including follicular B helper T cells (TFH). TIGIT has been shown to bind PVR with high affinity; this binding is thought to assist interactions between TFH and dendritic cells to regulate T cell dependent B cell responses. [taken from NCBI Entrez Gene (Gene ID: 201633)].
T-cell immunoreceptor with Ig and ITIM domains•
V-set and immunoglobulin domain containing 9•
V-set and immunoglobulin domain-containing protein 9•
V-set and transmembrane domain containing 3•
V-set and transmembrane domain-containing protein 3•
Washington University cell adhesion molecule•