RING-finger protein 138 (RNF138) is an E3 ubiquitin ligase. Together with NLK, RNF138 is involved in the ubiquitination and degradation of TCF/LEF. RNF138 also exhibits auto-ubiquitination activity in combination with UBE2K. RNF138 may act as a negative regulator in the Wnt/beta-catenin-mediated signaling pathway [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/ Q8WVD3].
E3 ubiquitin-protein ligase RNF138•
nemo-like kinase associated ring finger protein•
Nemo-like kinase-associated RING finger protein•
NLK-associated RING finger protein•
RING finger protein 138•
ring finger protein 138, E3 ubiquitin protein ligase•
RING-type E3 ubiquitin transferase RNF138•
testicular tissue protein Li 165•More...Less...