Come Visit Us at AACR! Booth #2141.

PNP Antibody

Purine nucleoside phosphorylase (PNP) is an enzyme which reversibly catalyzes the phosphorolysis of purine nucleosides. The PNP enzyme is trimeric, containing three identical subunits. Mutations which result in nucleoside phosphorylase deficiency result in defective T-cell (cell-mediated) immunity but can also affect B-cell immunity and antibody responses. Neurologic disorders may also be apparent in patients with immune defects. A known polymorphism at aa position 51 that does not affect enzyme activity has been described [taken from NCBI Entrez Gene (Gene ID: 4860)].
purine nucleoside phosphorylase
Purine nucleoside phosphorylase
:  epididymis secretory sperm binding protein Li 156an HEL-S-156an inosine phosphorylase inosine-guanosine phosphorylase NP PNP PRO1837 PUNP purine nucleoside phosphorylase purine-nucleoside:orthophosphate ribosyltransferase
Ordering Information
Between 239 and 289