PARD3 Antibody

Partitioning defective 3 homolog (Par3) is an adapter protein involved in asymmetrical cell division and cell polarization processes. It seems to play a central role in the formation of epithelial tight junctions and targets the phosphatase PTEN to cell junctions (By similarity). Par3 association with PARD6B may prevent the interaction of PARD3 with F11R/JAM1, thereby preventing tight junction assembly. The PARD6-PARD3 complex links GTP-bound Rho small GTPases to atypical protein kinase C proteins. Par3 is required for establishment of neuronal polarity and normal axon formation in cultured hippocampal neurons [taken from the Universal Protein Resource (UniProt)].
par-3 family cell polarity regulator
Partitioning defective 3 homolog
:  ASIP atypical PKC isotype-specific interacting protein atypical PKC isotype-specific-interacting protein Baz Bazooka CTCL tumor antigen se2-5 PAR3 PAR-3 par-3 (partitioning defective 3, C.elegans) homolog par-3 family cell polarity regulator alpha par-3 partitioning defective 3 homolog par-3 partitioning defective 3 homolog (C. elegans) PAR3alpha PAR3-alpha PARD-3 PARD3A PPP1R118 protein phosphatase 1, regulatory subunit 118 SE2-5L16 SE2-5LT1 SE2-5T2 More... Less...
Ordering Information
Human, Mouse
Between 1306 to 1356