Due to inclement weather, Bethyl will be closed Tuesday, January 16 and re-open Wednesday, January 17th at noon. Orders will not be processed until Bethyl re-opens. This is a developing weather situation and may continue to change. Thank you!
GEF-H1 (guanine nucleotide exchange factor H1) is a microtubule regulated guanine nucleotide exchange factor for the RhoA GTPase. It catalyzes the exchange of GDP for GTP by Rho in response to microtubule destabilization. GEF-H1 has shown to be regulated during cytokinesis and plays a role in the cleavage furrow.