CDK5RAP3 Antibody

CDK5RAP3 (CDK5 regulatory subunit-associated protein 3) was identified as a protein that associates with the activating subunit of Cdk5, p25NCK5A. Cdk5 is a brain specific cyclin-dependent kinase important to mammalian brain development; however CDK5RAP3 appears to be widely expressed in human tissues. CDK5RAP3 appears to exhibit functions that extend beyond its association with Cdk5. CDK5RAP3 is involved in modulating the G2/M DNA damage checkpoint and can associate with and regulate the Cdk1-cyclin B1 complex. CDK5RAP3 has also been demonstrated to interact with and regulate the tumor suppressor ARF (alternative reading frame) to further play a role in cell cycle progression.
CDK5RAP3
CDK5 regulatory subunit associated protein 3
CDK5 regulatory subunit-associated protein 3
:  C53 CDK5 activator-binding protein C53 CDK5 regulatory subunit associated protein IC53-2 FLJ13660 HSF-27 IC53 ischemic heart CDK5 activator-binding protein C53 LXXLL/leucine-zipper-containing ARFbinding protein LXXLL/leucine-zipper-containing ARF-binding protein LZAP MST016 OK/SW-cl.114 PP1553 Protein HSF-27 More... Less...
Product
Specifications
Ordering Information
Human
WB
Between 275 and 325
$339
$229
$99
Human
WB, IP
Between 450 and C-term
$339
$229
$99
Human
WB, IP
Includes: 1 each of A300-870A and A300-871A
$472
Includes: 1 each of A300-870A and A300-871A