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PAM Antibody

In addition to its possible functions as a facilitator of Myc activated transcription, PAM (protein associated with Myc) has also been shown to play a role in mTOR signaling. PAM functions as an E3 ubiquitin ligase for tuberin (TSC2), a negative regulator of the mTOR pathway. Additionally PAM has been shown to function as a guanosine exchange factor (GEF) for Rheb and to facilitate sphingosine-1-phosphate signaling in the mTOR pathway.
MYC binding protein 2, E3 ubiquitin protein ligase
E3 ubiquitin-protein ligase MYCBP2
:  E3 ubiquitin-protein ligase MYCBP2 Highwire myc-binding protein 2 Myc-bp2 PAM pam/highwire/rpm-1 protein Phr protein associated with Myc RING-type E3 ubiquitin transferase MYCBP2
Ordering Information
between 2425 and 2475