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Search Results for "Epsin 1"

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Rabbit anti-Epsin 1 Antibody
Bethyl Laboratories Catalog # A304-524A-T A304-524A

Validated

Rabbit anti-Epsin 1 Antibody

Validation Performed

All Bethyl Laboratories® antibodies are validated to meet our strict performance standards.

Learn more about the validation performed

Documents (4) Citations ()

Target: Epsin 1

Reactivity: Human

Applications:

Host: Rabbit

Clonality: Polyclonal

Conjugate:

Purity:

2 Figures

parentCodeBETHYL-A304-524

Bulk Request

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Product has been discontinued
Rabbit anti-Epsin 1 Antibody
Bethyl Laboratories Catalog # A304-525A-T A304-525A

Validated

Rabbit anti-Epsin 1 Antibody

Validation Performed

All Bethyl Laboratories® antibodies are validated to meet our strict performance standards.

Learn more about the validation performed

Documents (4)

Target: Epsin 1

Reactivity: Human, Mouse

Applications:

Host: Rabbit

Clonality: Polyclonal

Conjugate:

Purity:

2 Figures

parentCodeBETHYL-A304-525

Bulk Request

For ordering information, see our International Distributors

Distributors

Product has been discontinued
Rabbit anti-EpsinR Antibody
Bethyl Laboratories Catalog # A301-926A A301-926A-T

Validated

Rabbit anti-EpsinR Antibody

Validation Performed

All Bethyl Laboratories® antibodies are validated to meet our strict performance standards.

Learn more about the validation performed

Documents (3) Citations ()

Target: EpsinR

Reactivity: Human, Mouse

Applications:

Host: Rabbit

Clonality: Polyclonal

Conjugate:

Purity:

1 Figure

parentCodeBETHYL-A301-926

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For ordering information, see our International Distributors

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Product has been discontinued
Rabbit anti-EpsinR Antibody
Bethyl Laboratories Catalog # A301-925A-T A301-925A

Validated

Rabbit anti-EpsinR Antibody

Validation Performed

All Bethyl Laboratories® antibodies are validated to meet our strict performance standards.

Learn more about the validation performed

Documents (3)

Target: EpsinR

Reactivity: Human

Applications:

Host: Rabbit

Clonality: Polyclonal

Conjugate:

Purity:

1 Figure

parentCodeBETHYL-A301-925

Bulk Request

For ordering information, see our International Distributors

Distributors

Product has been discontinued

Programmed Cell Death-1 (PD-1)
Aliyah Weinstein, Ph.D.

Article

Programmed cell death-1 (PD-1) is an immune checkpoint molecule that belongs to the CD28 family, which also includes CTLA-4. PD-1 is expressed on T cells and functions as a negative regulator of helper and effector T cell activity. Its ligands, PD-L1 and PD-L2, are members of the B7 family and are expressed by antigen presenting cells as well as tissue type-specific cells throughout the body and cancer cells. Binding of PD-1 to its ligands activates an intracellular signaling cascade that results in the dephosphorylation of the T cell receptor or of CD28¹, and the consequent reduction in T cell activity. In healthy individuals, this pathway tunes the immune system to protect against autoimmunity by suppressing effector T cells and promoting the activity of regulatory T cells (Tregs)^{2, 3}.

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