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Search Results for "Cyclin E1"

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Rabbit anti-Cyclin E1 Antibody
Bethyl Laboratories Catalog # A301-566A A301-566A-T

Validated

Rabbit anti-Cyclin E1 Antibody

Validation Performed

All Bethyl Laboratories® antibodies are validated to meet our strict performance standards.

Learn more about the validation performed

Documents (4) Citations ()

Target: Cyclin E1

Reactivity: Human

Applications:

Host: Rabbit

Clonality: Polyclonal

Conjugate:

Purity:

2 Figures

parentCodeBETHYL-A301-566

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Product has been discontinued
Rabbit anti-Cyclin E1 IHC Antibody
Bethyl Laboratories Catalog # IHC-00341 IHC-00341-T

Validated

Rabbit anti-Cyclin E1 IHC Antibody

Validation Performed

All Bethyl Laboratories® antibodies are validated to meet our strict performance standards.

Learn more about the validation performed

Documents (3) Citations ()

Target: Cyclin E1

Reactivity: Human

Applications:

Host: Rabbit

Clonality: Polyclonal

Conjugate:

Purity:

1 Figure

parentCodeBETHYL-IHC-00341

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Product has been discontinued
ELISA Starter Accessory Kit (contains BSA blocking buffer)
Bethyl Laboratories Catalog # E101

Documents (3) Citations (43)

Applications: ELISA

3 Figures

parentCodeBETHYL-ELISA-Accessories

$363.00

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TMB One Component Substrate
Bethyl Laboratories Catalog # E102

Documents (3) Citations (16)

Applications: ELISA

parentCodeBETHYL-ELISA-Accessories

$57.00

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UBA6: An E1 enzyme critical for hippocampal and amygdalar development
Jill R. Glausier, Ph.D.

Article

Protein turnover and degradation is an essential component for the proper functioning of all eukaryotic cells. Proteins are tagged for degradation by the addition of ubiquitin, a process which requires three distinct enzyme classes. The classes are E1, the ubiquitin-activating enzyme; E2, the ubiquitin-conjugating enzymes; and E3, the ubiquitin-protein ligases. Although many E2 and E3 enzymes exist, the canonical ubiquitination pathway has only one ubiquitin-activating E1 enzyme, termed UBE1. However, within the last decade, researchers have identified a second ubiquitin-activating E1 enzyme, termed UBA^{1, 2, 3}. UBA6 has both distinct and overlapping traits with UBE1. For example, these enzymes are able to activate ubiquitin but UBA6 is also able to activate the ubiquitin-like modifier, FAT10. Both E1 enzymes can interact with a population of E2 enzymes but only UBA6 interacts with the E2 enzyme USE1⁴.

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