Due to inclement weather, Bethyl will be closed Tuesday, January 16 and re-open Wednesday, January 17th at noon. Orders will not be processed until Bethyl re-opens. This is a developing weather situation and may continue to change. Thank you!
Constitutive photomorphogenic protein 1 (COP1) has been characterized in plants as a RING-finger-containing protein that functions to repress plant photomorphogenesis. In mammals, COP1 has been identified as an E3 ubiquitin ligase that negatively regulates p53 protein levels in unstressed cells. In response to DNA damage COP1 is phosphorylated by the ataxia telangiectasia mutated (ATM) protein kinase and is rapidly degraded releasing p53 to exert its tumor suppressor activities.
constitutive photomorphogenesis protein 1 homolog•
constitutive photomorphogenic protein 1•
constitutive photomorphogenic protein 1 (Arabidopsis)•
putative ubiquitin ligase COP1•
ring finger and WD repeat domain 2•
ring finger and WD repeat domain 2, E3 ubiquitin protein ligase•
RING finger and WD repeat domain protein 2•
RING finger protein 200•