/ ANTIBODIES/ANTISERA / Primary Antibodies / Rabbit anti-WWP1 Antibody
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Primary Antibodies  

Rabbit anti-WWP1 Antibody Affinity Purified

bethyl
Bethyl Laboratories

Catalog #

Validated
Citations (1)
Target:

WWP1

Reactivity:

Human

Applications:

IP

,

WB

Host:

Rabbit

Clonality:

Polyclonal

Format:

Whole IgG

Immunogen:

between 200 and 250

Isotype:

IgG

Conjugate:

Unconjugated

Purity:

Antigen Affinity Purified

100 µl (1000 µg/ml)

10 µl (1000 µg/ml)

Product Details

Specifications
Verified Reactivity

Human

Antigen Species

Human

Concentration
1000 µg/ml
Storage

2 - 8 °C

Shelf Life

1 year from date of receipt

Physical State
Liquid
Buffer

Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% Sodium Azide


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Additional Product Information

WW domain-containing protein 1 (WWP1) functions as an E3 ubiquitin-protein ligase. WWP1 ubiquitinates ERBB4 isoforms JM-A CYT-1 and JM-B CYT-1, KLF2, KLF5 and TP63 and promotes their proteasomal degradation. WWP1 also ubiquitinates and promotes degradation of TGFBR1; TGFBR1 ubiquitination is enhanced by SMAD7, and WWP1 also ubiquitinates SMAD7 as well as SMAD6. [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/ Q9H0M0].

11059

WWP1

WW domain containing E3 ubiquitin protein ligase 1

Q9H0M0

NEDD4-like E3 ubiquitin-protein ligase WWP1

Alternate Names

AIP5; atrophin-1 interacting protein 5; Atrophin-1-interacting protein 5; HECT-type E3 ubiquitin transferase WWP1; hSDRP1; NEDD4-like E3 ubiquitin-protein ligase WWP1; Nedd-4-like ubiquitin-protein ligase; TGIF-interacting ubiquitin ligase 1; Tiul1; WW domain-containing protein 1

Applications

All western blot analysis is performed using 5% Milk-TBST for blocking and as antibody diluent. Primary antibody is incubated overnight.

Western blots of cell lysates are performed using Goat anti-Rabbit IgG Heavy and Light Chain Antibody (Cat. No. A120-101P).

Western blots of immunoprecipitates are performed using Goat anti-Rabbit Light Chain HRP Conjugate (Cat. No. A120-113P) with 5% Normal Pig Serum (Cat. No. S100-020) added to the blocking buffer.