Rabbit anti-WRNIP1 Antibody Affinity Purified
Catalog #
WRNIP1
Human
IHC
,IP
,WB
Rabbit
Polyclonal
Whole IgG
between 400 and 450
IgG
Unconjugated
Antigen Affinity Purified
Product Details
Human
Mouse,
Rat
Human
2 - 8 °C
1 year from date of receipt
WRNIP1 (Werner helicase interacting protein 1) was identified as a protein that interacts with the N-terminal region of Werner protein (WRN). WRN is a RecQ DNA helicase important to DNA repair and is the causative gene of Werner syndrome (WS), an autosomal recessive disease characterized by premature aging. WRNIP1 has been shown to interact with DNA polymerase delta (pol delta) and play a role in pol delta-mediated DNA synthesis. Additionally, WRNIP1 has been shown to interact with polyubiquitin chains indicating a link between ubiquitination and the DNA repair pathway.
Alternate Names
ATPase WRNIP1; bA420G6.2; putative helicase RUVBL; Werner helicase-interacting protein 1; WHIP
Applications