/ ANTIBODIES/ANTISERA / Primary Antibodies / Rabbit anti-TPR Antibody
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Primary Antibodies  

Rabbit anti-TPR Antibody

Bethyl Laboratories®
Bethyl Laboratories®

Catalog #

Validated
Citations (4)
Target:

TPR

Reactivity:

Human

Applications:

IP

,

WB

Host:

Rabbit

Clonality:

Polyclonal

Format:

Whole IgG

Immunogen:

between 1650 and 1700

Isotype:

IgG

Conjugate:

Unconjugated

Purity:

Antigen Affinity Purified

100 µl (200 µg/ml)

10 µl (200 µg/ml)

Product Details

Specifications
Verified Reactivity

Human

Presumed Reactivity

Mouse,

Rat

Antigen Species

Human

Concentration
200 µg/ml
Storage

2 - 8 °C

Shelf Life

1 year from date of receipt

Physical State
Liquid
Buffer

Tris-buffered Saline containing 0.1% BSA and 0.09% Sodium Azide


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Additional Product Information

TPR (translocated promoter region) was identified in oncogenic fusions with the kinase domains of trk, met, and raf protooncogenes. TPR has also been identified as a candidate nuclear skeletal protein that localizes to nuclear pore-associated intranuclear filaments. TPR is part of an interchromasomal channel-based nuclear matrix that provides connectivity between the nuclear interior and periphery. It is implicated in intranuclear transport and export of mRNA and proteins.

7175

TPR

translocated promoter region, nuclear basket protein

P12270

Nucleoprotein TPR

Alternate Names

megator; NPC-associated intranuclear protein; nuclear pore complex-associated protein TPR; nucleoprotein TPR; translocated promoter region (to activated MET oncogene); translocated promoter region protein; tumor potentiating region

Applications

All western blot analysis is performed using 5% Milk-TBST for blocking and as antibody diluent. Primary antibody is incubated overnight.

Western blots of cell lysates are performed using Goat anti-Rabbit IgG Heavy and Light Chain Antibody (Cat. No. A120-101P).

Western blots of immunoprecipitates are performed using Goat anti-Rabbit Light Chain HRP Conjugate (Cat. No. A120-113P) with 5% Normal Pig Serum (Cat. No. S100-020) added to the blocking buffer.