Rabbit anti-TIMM8A Antibody Affinity Purified
Catalog #
TIMM8A
Human
IP
Rabbit
Polyclonal
Whole IgG
Between 1 and 50
IgG
Unconjugated
Antigen Affinity Purified
Product Details
Human
Human
2 - 8 °C
1 year from date of receipt
Translocase of inner mitochondrial membrane 8 homolog A (TIMM8A) is a translocase involved in the import and insertion of hydrophobic membrane proteins from the cytoplasm into the mitochondrial inner membrane. The TIMM8A gene is mutated in Mohr-Tranebjaerg syndrome/Deafness Dystonia Syndrome (MTS/DDS), and it is postulated that MTS/DDS is a mitochondrial disease caused by a defective mitochondrial protein import system. Defects in the TIMM8A gene also cause Jensen syndrome; an X-linked disease with opticoacoustic nerve atrophy and muscle weakness. Along with TIMM13, TIMM8A forms a 70 kDa heterohexamer [taken from NCBI Entrez Gene (Gene ID: 1678)].
Mitochondrial import inner membrane translocase subunit Tim8 A
Alternate Names
DDP; DDP1; deafness dystonia protein 1; deafness/dystonia peptide; DFN1; mitochondrial import inner membrane translocase subunit Tim8 A; MTS; TIM8; translocase of inner mitochondrial membrane 8 homolog A; X-linked deafness dystonia protein
Applications