Rabbit anti-TBLR1 Antibody Affinity Purified
Catalog #
TBLR1
Human
,Mouse
IHC
,IP
,WB
Rabbit
Polyclonal
Whole IgG
between 100 and 150
IgG
Unconjugated
Antigen Affinity Purified
Product Details
Mouse,
Human
Human
2 - 8 °C
1 year from date of receipt
TBLR1 is a six WD-40 repeat protein with high sequence homology to TBL1 (transducin beta-like protein 1) and is part of the SMRT (silencing mediator of retinoid and thyroid hormone receptors) and N-CoR (nuclear receptor corepressor) complexes that interact with nuclear receptors and repress transcription. Biochemical characterization of SMRT and N-CoR complexes demonstrate that SMRT and N-CoR are present in complexes that include HDAC3 (histone deacetylase 3), TBL1, and TBLR1. Association with HDAC3 indicates that these complexes may repress transcription through histone deacetylation and chromatin remodeling.
F-box-like/WD repeat-containing protein TBL1XR1
Alternate Names
C21; DC42; F-box-like/WD repeat-containing protein TBL1XR1; IRA1; MRD41; nuclear receptor co-repressor/HDAC3 complex subunit; nuclear receptor corepressor/HDAC3 complex subunit TBLR1; TBL1-related protein 1; TBLR1; Transducin beta-like 1X-related protein 1
Applications