Rabbit anti-TAF1 Antibody
Catalog #
TAF1
Human
,Mouse
IP
,WB
Rabbit
Polyclonal
Whole IgG
between 1800 and 1850
IgG
Unconjugated
Antigen Affinity Purified
Product Details
Mouse,
Human
Mouse,
Golden_hamster
Human
2 - 8 °C
1 year from date of receipt
Transcription initiation factor TFIID subunit 1 (TAF1) is the largest component and core scaffold of the TFIID basal transcription factor complex. TAF1 contains novel N- and C-terminal Ser/Thr kinase domains which can autophosphorylate or transphosphorylate other transcription factors. TAF1 phosphorylates TP53 on 'Thr-55' which leads to MDM2-mediated degradation of TP53. It also phosphorylates GTF2A1 and GTF2F1 on Ser residues. TAF1 possesses DNA-binding activity and is essential for progression of the G1 phase of the cell cycle [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/P21675].
Transcription initiation factor TFIID subunit 1
Alternate Names
BA2R; CCG1; CCGS; cell cycle gene 1 protein; cell cycle, G1 phase defect; complementation of cell cycle block, G1-to-S; DYT3; DYT3/TAF1; KAT4; MRXS33; NSCL2; N-TAF1; OF; P250; TAF(II)250; TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa; TAF2A; TAFII250; TAFII-250; TBP-associated factor 250 kDa; transcription factor TFIID p250 polypeptide; Transcription initiation factor TFIID 250 kDa subunit; transcription initiation factor TFIID subunit 1; XDP
Applications