Rabbit anti-SF3b145/SAP145 IHC Antibody
Catalog #
SF3b145/SAP145
Human
,Mouse
IHC
,IHC-IF
Rabbit
Polyclonal
Whole IgG
Between 775 and 825
IgG
Unconjugated
Antigen Affinity Purified
Product Details
Mouse,
Human
Horse,
Dog,
Pig,
Rabbit,
Bovine,
Monkey,
Rat
Human
2 - 8 °C
1 year from date of receipt
SF3b145/SAP145 is a 145 kDa subunit of the splicing factor 3B (SF3B) protein complex. The SF3B complex is composed of at least 8 subunits (SF3B1 through SF3B8). SF3A along with SF3B and a 12S RNA unit are components of the 17S U2 small nuclear ribonucleoprotein complex (U2 snRNP) involved in pre-mRNA splicing. In this complex SF3B2 interacts directly with SF3B4 and associates with the pre-mRNA upstream of the branch site at the anchoring site. SF3A and SF3B may play a role in anchoring the U2 snRNP to the pre-mRNA upstream of the intron’s branch site.
Alternate Names
Cus1; pre-mRNA splicing factor SF3b 145 kDa subunit; Pre-mRNA-splicing factor SF3b 145 kDa subunit; SAP 145; SAP145; SF3b1; SF3B145; SF3b150; spliceosome associated protein 145; Spliceosome-associated protein 145; splicing factor 3B subunit 2; splicing factor 3b, subunit 2, 145kD; splicing factor 3b, subunit 2, 145kDa
Applications
