Rabbit anti-SARA Antibody Affinity Purified
Catalog #
SARA
Human
IP
,WB
Rabbit
Polyclonal
Whole IgG
Between 1 and 50
IgG
Unconjugated
Antigen Affinity Purified
Product Details
Human
Human
2 - 8 °C
1 year from date of receipt
Smad anchor for receptor activation (SARA) is an early endosomal protein that functions to recruit SMAD2/SMAD3 to intracellular membranes and to the TGF-beta receptor. SARA plays a significant role in TGF-mediated signaling by regulating the subcellular location of SMAD2 and SMAD3 and modulating the transcriptional activity of the SMAD3/SMAD4 complex. SARA is possibly associated with TGF-beta receptor internalization [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/O95405].
Alternate Names
hSARA; MAD, mothers against decapentaplegic homolog interacting protein, receptor activation anchor; MADH-interacting protein; MADHIP; Mothers against decapentaplegic homolog-interacting protein; novel serine protease; NSP; PPP1R173; protein phosphatase 1, regulatory subunit 173; Receptor activation anchor; SARA; smad anchor for receptor activation; SMADIP; zinc finger FYVE domain-containing protein 9; zinc finger, FYVE domain containing 9
Applications