Rabbit anti-RAF1/c-Raf Recombinant Monoclonal Antibody [BLR289L]
Catalog #
RAF1/c-Raf
Human
,Mouse
Flow Cyt
,IP
,WB
Rabbit
Recombinant Monoclonal
BLR289L
Whole IgG
between 300 and 350
IgG
Unconjugated
Purified
Product Details
Mouse,
Human
Human
2 - 8 °C
1 year from date of receipt
RAF1 is a mitogen activated kinase kinase kinase (MAPKKK). In response to extracellular signals, RAF1 phosphorylates the MEK1 and MEK2 MAP kinase kinases. MEK1 and MEK2 subsequently phosphorylate and activate the ERK1 and ERK2 MAP kinases to exert pleiotropic effects on cellular functions such as growth, division, differentiation, motility, and apoptosis. RAF1 associates with the Ras family of membrane GTPases and functions downstream of Ras activity.
RAF proto-oncogene serine/threonine-protein kinase
Alternate Names
CMD1NN;CRAF;c-Raf;C-Raf proto-oncogene, serine/threonine kinase;NS5;Oncogene RAF1;proto-oncogene c-RAF;raf proto-oncogene serine/threonine protein kinase;RAF proto-oncogene serine/threonine-protein kinase;Raf-1;v-raf-1 murine leukemia viral oncogene homolog 1;v-raf-1 murine leukemia viral oncogene-like protein 1
Applications