Rabbit anti-PYGL Antibody Affinity Purified
Catalog #
PYGL
Human
,Mouse
IP
,WB
Rabbit
Polyclonal
Whole IgG
Between 797 and 847
IgG
Unconjugated
Antigen Affinity Purified
Product Details
Mouse,
Human
Human
2 - 8 °C
1 year from date of receipt
Glycogen phosphorylase, liver form, (PYGL) encodes a homodimeric protein that catalyses the cleavage of alpha-1,4-glucosidic bonds to release glucose-1-phosphate from liver glycogen stores. This protein switches from inactive phosphorylase B to active phosphorylase A by phosphorylation of serine residue 15. Activity of this enzyme is further regulated by multiple allosteric effectors and hormonal controls. Humans have three glycogen phosphorylase genes that encode distinct isozymes that are primarily expressed in liver, brain and muscle, respectively. The liver isozyme serves the glycemic demands of the body in general while the brain and muscle isozymes supply just those tissues [taken from NCBI Entrez Gene (Gene ID: 5836)].
Alternate Names
glycogen phosphorylase, liver form; GSD6; phosphorylase, glycogen, liver
Applications