Rabbit anti-PTRH2/BIT1 Antibody Affinity Purified
Catalog #
PTRH2/BIT1
Human
WB
Rabbit
Polyclonal
Whole IgG
Between 129 and 179
IgG
Unconjugated
Antigen Affinity Purified
Product Details
Human
Human
2 - 8 °C
1 year from date of receipt
Peptidyl-tRNA hydrolase 2 (PTRH2) is a mitochondrial protein with two putative domains, an N-terminal mitochondrial localization sequence, and a UPF0099 domain. In vitro assays suggest that this protein possesses peptidyl-tRNA hydrolase activity, to release the peptidyl moiety from tRNA, thereby preventing the accumulation of dissociated peptidyl-tRNA that could reduce the efficiency of translation. This protein also plays a role regulating cell survival and death. It promotes survival as part of an integrin-signaling pathway for cells attached to the extracellular matrix (ECM), but also promotes apoptosis in cells that have lost their attachment to the ECM, a process called anoikos [taken from NCBI Entrez Gene (Gene ID: 51651)].
Alternate Names
bcl-2 inhibitor of transcription 1; BIT1; CFAP37; CGI-147; cilia and flagella associated protein 37; IMNEPD; peptidyl-tRNA hydrolase 2, mitochondrial; PTH; PTH 2; PTH2
Applications