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Rabbit anti-PTPN12 IHC Antibody Affinity Purified
Bethyl Laboratories
Catalog #
Validated
Target:
PTPN12
Reactivity:
Human
,Mouse
Applications:
IHC
,IHC-IF
Host:
Rabbit
Clonality:
Polyclonal
Format:
Whole IgG
Immunogen:
Between 760 and 780
Isotype:
IgG
Conjugate:
Unconjugated
Purity:
Antigen Affinity Purified
100 µl (50+ slides)
10 µl (5+ slides)
Product Details
Specifications
Verified Reactivity
Mouse,
Human
Presumed Reactivity
Guinea Pig,
Horse,
Dog,
Rabbit,
Bovine,
Monkey,
Rat
Antigen Species
Human
Concentration
250 µg/ml
Storage
2 - 8 °C
Shelf Life
1 year from date of receipt
Physical State
Liquid
Buffer
Production Procedures
Antibody was affinity purified using an epitope specific to PTPN12 immobilized on solid support.
The epitope recognized by IHC-00260 maps to a region between residue 760 and 780 of human protein tyrosine phosphatase, non-receptor type 12 using the numbering given in entry NP_002826.2 (GeneID 5782).
Immunoglobulin concentration was determined using Beer’s Law where 1mg/mL IgG has an A280 of 1.4.
Antibody was affinity purified using an epitope specific to PTPN12 immobilized on solid support.
The epitope recognized by IHC-00260-T maps to a region between residue 760 and 780 of human protein tyrosine phosphatase, non-receptor type 12 using the numbering given in entry NP_002826.2 (GeneID 5782).
Immunoglobulin concentration was determined using Beer’s Law where 1mg/mL IgG has an A280 of 1.4.
Additional Product Information
PTPN12 is a cytosolic protein tyrosine phosphatase (PTP) that contains a C-terminal PEST motif and plays an important role in cytoskeletal organization, immune cell activation, apoptosis, and embryonic development. PTPN12 appears to contribute to these cellular processes through its interaction with a variety of signaling and cytoskeletal-associated proteins. The recent discovery that PTPN12 is modulated by caspase-3 cleavage has led to the analysis of the role of PTPN12 and other PTPs as regulators of apoptosis.
Tyrosine-protein phosphatase non-receptor type 12
Alternate Names
protein-tyrosine phosphatase G1; PTPG1; PTP-PEST; tyrosine-protein phosphatase non-receptor type 12
Applications
