Rabbit anti-PSMB5 Antibody Affinity Purified
Catalog #
PSMB5
Human
IHC
,IP
,WB
Rabbit
Polyclonal
Whole IgG
Between 213 and 263
IgG
Unconjugated
Antigen Affinity Purified
Product Details
Human
Human
2 - 8 °C
1 year from date of receipt
PSMB5 [proteasome (prosome, macropain) subunit, beta type, 5)] is a member of the proteasome B-type family, also known as the T1B family, that is a 20S core beta subunit in the proteasome. The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This catalytic subunit is not present in the immunoproteasome and is replaced by catalytic subunit 3i (proteasome beta 8 subunit) [taken from NCBI Entrez Gene (Gene ID: 5693)].
Alternate Names
LMPX; macropain epsilon chain; MB1; multicatalytic endopeptidase complex epsilon chain; proteasome (prosome, macropain) subunit, beta type, 5; proteasome beta 5 subunit; proteasome catalytic subunit 3; proteasome chain 6; proteasome epsilon chain; proteasome subunit beta type-5; proteasome subunit MB1; proteasome subunit X; proteasome subunit, beta type, 5; PSX large multifunctional protease X; testicular tissue protein Li 153; X
Applications