Rabbit anti-Presenilin-2 Antibody
Catalog #
Presenilin-2
Human
IHC
,IP
,WB
Rabbit
Polyclonal
Whole IgG
Between 275 and 325
IgG
Unconjugated
Antigen Affinity Purified
Product Details
Human
Mouse,
Pig,
Bovine,
Rat
Human
2 - 8 °C
1 year from date of receipt
Presenilin-2 is a probable catalytic subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors and APP (beta-amyloid precursor protein). Presenilin-2 requires the other members of the gamma-secretase complex to have a protease activity. It may play a role in intracellular signaling and gene expression or in linking chromatin to the nuclear membrane. It may function in the cytoplasmic partitioning of proteins [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/P49810].
Alternate Names
AD3L; AD3LP; AD4; AD5; Alzheimer disease 4; CMD1V; E5-1; presenilin-2; PS2; PS-2; STM2; STM-2
Applications