Rabbit anti-PPIP5K2 Antibody Affinity Purified
Catalog #
PPIP5K2
Human
IP
Rabbit
Polyclonal
Whole IgG
Between 1 and 50
IgG
Unconjugated
Antigen Affinity Purified
Product Details
Human
Human
2 - 8 °C
1 year from date of receipt
PPIP5K2 is a bifunctional inositol kinase that acts in concert with the IP6K kinases IP6K1, IP6K2 and IP6K3 to synthesize the diphosphate group-containing inositol pyrophosphates diphosphoinositol pentakisphosphate, PP-InsP5, and bis-diphosphoinositol tetrakisphosphate, (PP)2-InsP4. PP-InsP5 and (PP)2-InsP4, also respectively called InsP7 and InsP8, regulate a variety of cellular processes, including apoptosis, vesicle trafficking, cytoskeletal dynamics, exocytosis, insulin signaling and neutrophil activation. PPPIP5K2 phosphorylates inositol hexakisphosphate (InsP6) at positions 1 or 3 to produce PP-InsP5 which is in turn phosphorylated by IP6Ks to produce (PP)2-InsP4. Alternatively, PPIP5K2 phosphorylates at position 1 or 3 PP-InsP5, produced by IP6Ks from InsP6, to produce (PP)2-InsP4 [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/O43314].
Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 2
Alternate Names
CFAP160; deafness, autosomal recessive 100; DFNB100; Diphosphoinositol pentakisphosphate kinase 2; HISPPD1; histidine acid phosphatase domain-containing protein 1; hsVIP2; inositol heptaphosphate kinase 2; inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 2; insP6 and PP-IP5 kinase 2; IP7K2; VIP1 homolog 2; VIP2
Applications