/ ANTIBODIES/ANTISERA / Primary Antibodies / Rabbit anti-PINX1 Antibody
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Primary Antibodies  

Rabbit anti-PINX1 Antibody Affinity Purified

Bethyl Laboratories®
Bethyl Laboratories®

Catalog #

Validated
Target:

PINX1

Reactivity:

Human

Applications:

IHC

,

IP

,

WB

Host:

Rabbit

Clonality:

Polyclonal

Format:

Whole IgG

Immunogen:

Between 225 and 275

Isotype:

IgG

Conjugate:

Unconjugated

Purity:

Antigen Affinity Purified

100 µl (1000 µg/ml)

10 µl (1000 µg/ml)

Product Details

Specifications
Verified Reactivity

Human

Antigen Species

Human

Concentration
1000 µg/ml
Storage

2 - 8 °C

Shelf Life

1 year from date of receipt

Physical State
Liquid
Buffer

Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% Sodium Azide


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Additional Product Information

PINX1 is a microtubule-binding protein essential for faithful chromosome segregation. PINX1 mediates TRF1 and TERT accumulation in nucleolus and enhances TRF1 binding to telomeres. It inhibits telomerase activity and may inhibit cell proliferation and act as tumor suppressor [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q96BK5].

54984

PINX1

PIN2 (TERF1) interacting telomerase inhibitor 1

Q96BK5

PIN2/TERF1-interacting telomerase inhibitor 1

Alternate Names

67-11-3 protein; Gno1; hepatocellular carcinoma-related putative tumor suppressor; liver-related putative tumor suppressor; LPTL; LPTS; PIN2/TERF1-interacting telomerase inhibitor 1; PIN2-interacting protein 1; pin2-interacting protein X1; protein 67-11-3; Pxr1; TRF1-interacting protein 1

Applications

All western blot analysis is performed using 5% Milk-TBST for blocking and as antibody diluent. Primary antibody is incubated overnight.

Western blots of cell lysates are performed using Goat anti-Rabbit IgG Heavy and Light Chain Antibody (Cat. No. A120-101P).

Western blots of immunoprecipitates are performed using Goat anti-Rabbit Light Chain HRP Conjugate (Cat. No. A120-113P) with 5% Normal Pig Serum (Cat. No. S100-020) added to the blocking buffer.