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Rabbit anti-Phospho MCM2 (S108) IHC Antibody Affinity Purified
Bethyl Laboratories
Catalog #
Validated
Target:
MCM2 Phospho (S108)
Reactivity:
Human
,Mouse
Applications:
IHC
,IHC-IF
Host:
Rabbit
Clonality:
Polyclonal
Format:
Whole IgG
Immunogen:
Surrounding serine 108
Isotype:
IgG
Conjugate:
Unconjugated
Purity:
Antigen Affinity Purified
100 µl (50+ slides)
10 µl (5+ slides)
Product Details
Specifications
Verified Reactivity
Mouse,
Human
Presumed Reactivity
Guinea Pig,
Horse,
Zebra Finch,
Turkey,
Dog,
Chicken,
Pig,
Rabbit,
Bovine,
Monkey,
Rat
Antigen Species
Human
Concentration
100 µg/ml
Storage
2 - 8 °C
Shelf Life
1 year from date of receipt
Physical State
Liquid
Buffer
Production Procedures
Antibody was affinity purified using an epitope specific to Phospho-MCM2 (Ser 108) immobilized on solid support.
Immunogen for IHC-00014 was a synthetic phosphorylated peptide, which represented a portion of human Minichromosomal Maintenance Deficient 2 surrounding Serine 108 according to the numbering given in entry NP_0045117.2 (GeneID 4171).
Antibody was affinity purified using an epitope specific to Phospho-MCM2 (Ser 108) immobilized on solid support. Immunogen for IHC-00014-T was a synthetic phosphorylated peptide, which represented a portion of human Minichromosomal Maintenance Deficient 2 surrounding Serine 108 according to the numbering given in entry NP_0045117.2 (GeneID 4171).
Additional Product Information
The MCM (Mini-Chromosome Maintenance) complex is a key component of the pre-replication complex involved in replication licensing which restricts DNA replication to only once per cell cycle. The MCM complex is a heterohexamer of MCM2, MCM3, MCM4, MCM5, MCM6, and MCM7. MCM2 interacts with the core MCM complex (MCM4, 6, and 7) to regulate its helicase activity.
DNA replication licensing factor MCM2
Alternate Names
BM28; CCNL1; cdc19; CDCL1; cell devision cycle-like 1; cyclin-like 1; D3S3194; DFNA70; DNA replication licensing factor MCM2; minichromosome maintenance deficient 2 (mitotin); minichromosome maintenance protein 2 homolog; MITOTIN; nuclear protein BM28
Applications
