Rabbit anti-PCNA IHC Antibody Affinity Purified
Catalog #
PCNA
Human
,Mouse
IHC
,IHC-IF
Rabbit
Polyclonal
Whole IgG
Between 225 and C-term
IgG
Unconjugated
Antigen Affinity Purified
Product Details
Mouse,
Human
Guinea Pig,
Sheep,
Dog,
Pig,
Rabbit,
Bovine,
Monkey,
Rat
Human
2 - 8 °C
1 year from date of receipt
Antibody was affinity purified using an epitope specific to PCNA immobilized on solid support.
The epitope recognized by IHC-00012 maps to a region between residue 225 and the C-terminus (residue 261) of human proliferating cell nuclear antigen using the numbering given in entry NP 002583.1 (GeneID 5111).
Antibody was affinity purified using an epitope specific to PCNA immobilized on solid support.
The epitope recognized by IHC-00012-T maps to a region between residue 225 and the C-terminus (residue 261) of human proliferating cell nuclear antigen using the numbering given in entry NP 002583.1 (GeneID 5111).
PCNA (Proliferating Cell Nuclear Antigen) was first identified as a factor expressed in the nuclei of replicating cells. PCNA plays a role in both DNA synthesis and repair. PCNA functions as a processivity factor for DNA polymerase by acting as a DNA clamp that tethers the polymerase catalytic units to the DNA template. The structure of PCNA is that of a trimeric ring that encircles and slides along replicating DNA. PCNA interacts with and is regulated by several proteins involved in cell cycle control and check point processes.
Alternate Names
ATLD2; cyclin; DNA polymerase delta auxiliary protein; PCNA; proliferating cell nuclear antigen
Applications