Rabbit anti-Parafibromin Antibody Affinity Purified
Catalog #
Parafibromin
Human
,Mouse
IP
,WB
Rabbit
Polyclonal
Whole IgG
between 250 and 300
IgG
Unconjugated
Antigen Affinity Purified
Product Details
Mouse,
Human
Rat
Human
2 - 8 °C
1 year from date of receipt
Parafibromin, also known as HRPT2 (hyperparathyroidism 2 protein), has been identified as a tumor suppressor that is associated with hyperparathyroidism-jaw tumor syndrome, an autosomal dominant disease characterized by hyperparathyroidism due to parathyroid tumors and ossifying fibromas of the mandible and maxilla. Parafibromin is a component of the PAF1 complex that associates with RNA polymerase II and plays a role in mRNA 3’-end processing and transcription elongation. Parafibromin has been demonstrated to function as an inhibitor of the cell cycle.
Alternate Names
C1orf28; cell division cycle 73 Paf1/RNA polymerase II complex component-like protein; cell division cycle 73, Paf1/RNA polymerase II complex component, homolog; cell division cycle protein 73 homolog; FIHP; HPTJT; HRPT1; HRPT2; hyperparathyroidism 2 protein; HYX; Paf1/RNA polymerase II complex component; parafibromin
Applications