Rabbit anti-PABPN1 Antibody Affinity Purified
Catalog #
PABPN1
Human
,Mouse
IHC
,IP
,WB
Rabbit
Polyclonal
Whole IgG
between 1 and 50
IgG
Unconjugated
Antigen Affinity Purified
Product Details
Mouse,
Human
Bovine
Human
2 - 8 °C
1 year from date of receipt
Polyadenylate binding protein, nuclear 1 (PABPN1) is involved in the 3'-end formation of mRNA precursors (pre-mRNA) by the addition of a poly(A) tail of 200-250 nt to the upstream cleavage product. PABPN1 stimulates poly(A) polymerase (PAPOLA) conferring processivity on the poly(A) tail elongation reaction and also controls the poly(A) tail length. PABPN1 increases the affinity of poly(A) polymerase for RNA and is also present at various stages of mRNA metabolism including nucleocytoplasmic trafficking and nonsense-mediated decay (NMD) of mRNA [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q86U42].
Alternate Names
Nuclear poly(A)-binding protein 1; OPMD; PAB2; PABII; PABP2; PABP-2; poly(A) binding protein 2; poly(A) binding protein II; Poly(A)-binding protein 2; Poly(A)-binding protein II; Polyadenylate-binding nuclear protein 1; polyadenylate-binding protein 2
Applications