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Primary Antibodies

Rabbit anti-Optineurin Antibody Affinity Purified

Name: Rabbit anti-Optineurin Antibody
Brand: Bethyl Laboratories
SKU: A301-829A
Price: 121 USD

Bethyl Laboratories

Catalog #

Citations (4)

Target:

Optineurin

Reactivity:

Human

Applications:

Host:

Rabbit

Clonality:

Polyclonal

Format:

Whole IgG

Immunogen:

between 1 and 50

Isotype:

IgG

Conjugate:

Unconjugated

Purity:

Antigen Affinity Purified

100 µl (1000 µg/ml)

10 µl (1000 µg/ml)

Product Details

Specifications

Verified Reactivity

Human

Presumed Reactivity

Monkey

Antigen Species

Human

Concentration

1000 µg/ml

Storage

2 - 8 °C

Shelf Life

1 year from date of receipt

Physical State

Liquid

Buffer

Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% Sodium Azide

Request Formulation Change

Additional Product Information

Defects in optineurin have been linked to glaucoma. In the cell, optineurin localizes to the Golgi and associates with markers of the endocytic pathway. A role in membrane trafficking and golgi function has been proposed due to its association with the actin-based motor protein myosin VI and its function as an effector protein of the small GTPase Rab8.

Gene ID:

10133

Gene Symbol:

OPTN

Gene Name:

optineurin

Uniprot ID:

Q96CV9

Protein Name:

Optineurin

Alternate Names

ALS12; E3-14.7K-interacting protein; FIP2; FIP-2; GLC1E; HIP7; HIP-7; Huntingtin interacting protein L; huntingtin yeast partner L; huntingtin-interacting protein 7; huntingtin-interacting protein L; HYPL; nemo-related protein; NRP; optic neuropathy-inducing protein; optineurin; TFIIIA-INTP; transcription factor IIIA-interacting protein; transcrption factor IIIA-interacting protein; tumor necrosis factor alpha-inducible cellular protein containing leucine zipper domains

Applications

All western blot analysis is performed using 5% Milk-TBST for blocking and as antibody diluent. Primary antibody is incubated overnight.

Western blots of immunoprecipitates are performed using Goat anti-Rabbit Light Chain HRP Conjugate (Cat. No. A120-113P) with 5% Normal Pig Serum (Cat. No. S100-020) added to the blocking buffer.