Rabbit anti-NXF1 Antibody
Catalog #
NXF1
Human
,Mouse
IP
,WB
Rabbit
Polyclonal
Whole IgG
Between 569 and 619
IgG
Unconjugated
Antigen Affinity Purified
Product Details
Mouse,
Human
Bovine,
Rat
Human
2 - 8 °C
1 year from date of receipt
Nuclear RNA export factor 1 (NXF1) is one member of a family of nuclear RNA export factor genes. Common domain features of this family are a noncanonical RNP-type RNA-binding domain (RBD), 4 leucine-rich repeats (LRRs), a nuclear transport factor 2 (NTF2)-like domain that allows heterodimerization with NTF2-related export protein-1 (NXT1), and a ubiquitin-associated domain that mediates interactions with nucleoporins. The LRRs and NTF2-like domains are required for export activity. NXF1 shuttles between the nucleus and the cytoplasm and binds in vivo to poly(A)+ RNA. It is the vertebrate homologue of the yeast protein Mex67p [taken from NCBI Entrez Gene (Gene ID: 10482)].
Alternate Names
MEX67; mRNA export factor TAP; nuclear RNA export factor 1; TAP; tip associating protein; tip-associated protein; Tip-associating protein
Applications