Rabbit anti-NPAT Antibody Affinity Purified
Catalog #
NPAT
Human
IHC
,IP
Rabbit
Polyclonal
Whole IgG
between 700 and 750
IgG
Unconjugated
Antigen Affinity Purified
Product Details
Human
Human
2 - 8 °C
1 year from date of receipt
NPAT (nuclear protein of the ataxia telangiectasia mutated locus) is required for progression through the G1 and S phases of the cell cycle and for S phase entry. It activates transcription of the histone H2A, histone H2B, histone H3 and histone H4 genes in conjunction with MIZF. NPAT also positively regulates the ATM, MIZF and PRKDC promoters. Transcriptional activation may be accomplished at least in part by the recruitment of the NuA4 histone acetyltransferase (HAT) complex to target gene promoters [taken from the Universal Protein Resource (UniProt) ww.uniprot.org/uniprot/Q14207].
Alternate Names
E14; E14/NPAT; nuclear protein of the ataxia telangiectasia mutated locus; nuclear protein of the ATM locus; nuclear protein, ataxia-telangiectasia locus; nuclear protein, co-activator of histone transcription; p220; protein NPAT
Applications