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Primary Antibodies

Rabbit anti-NIR Antibody Affinity Purified

Name: Rabbit anti-NIR Antibody
Brand: Bethyl Laboratories
SKU: A304-530A
Price: 121 USD

Bethyl Laboratories

Catalog #

Target:

NIR

Reactivity:

Human

Applications:

Host:

Rabbit

Clonality:

Polyclonal

Format:

Whole IgG

Immunogen:

Between 699 and 749

Isotype:

IgG

Conjugate:

Unconjugated

Purity:

Antigen Affinity Purified

100 µl (1000 µg/ml)

10 µl (1000 µg/ml)

Product Details

Specifications

Verified Reactivity

Human

Antigen Species

Human

Concentration

1000 µg/ml

Storage

2 - 8 °C

Shelf Life

1 year from date of receipt

Physical State

Liquid

Buffer

Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% Sodium Azide

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Additional Product Information

Novel INHAT repressor (NIR) acts as an inhibitor of histone acetyltransferase activity; it prevents acetylation of all core histones by the EP300/p300 histone acetyltransferase at p53/TP53-regulated target promoters in a histone deacetylases (HDAC)-independent manner. NIR acts as a transcription corepressor of p53/TP53- and TP63-mediated transactivation of the p21/CDKN1A promoter. It is involved in the regulation of p53/TP53-dependent apoptosis and it associates together with TP63 isoform TA*-gamma to the p21/CDKN1A promoter [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q9Y3T9].

Gene ID:

26155

Gene Symbol:

NOC2L

Gene Name:

NOC2 like nucleolar associated transcriptional repressor

Uniprot ID:

Q9Y3T9

Protein Name:

Nucleolar complex protein 2 homolog

Alternate Names

NET15; NET7; NIR; NOC2L nucleolar associated transcriptional repressor; NOC2-like protein; novel INHAT (inhibitor of histone acetyltransferase) repressor; novel INHAT repressor; nucleolar complex associated 2 homolog; nucleolar complex protein 2 homolog; PPP1R112; protein NOC2 homolog; protein phosphatase 1, regulatory subunit 12

Applications

All western blot analysis is performed using 5% Milk-TBST for blocking and as antibody diluent. Primary antibody is incubated overnight.

Western blots of cell lysates are performed using Goat anti-Rabbit IgG Heavy and Light Chain Antibody (Cat. No. A120-101P).

Rabbit anti-NIR Antibody Affinity Purified

Catalog #

NIR

Human

IHC

WB

Rabbit

Polyclonal

Whole IgG

Between 699 and 749

IgG

Unconjugated

Antigen Affinity Purified

Human

Human

2 - 8 °C

1 year from date of receipt

Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% Sodium Azide

26155

NOC2L

NOC2 like nucleolar associated transcriptional repressor

Q9Y3T9

Nucleolar complex protein 2 homolog

All western blot analysis is performed using 5% Milk-TBST for blocking and as antibody diluent. Primary antibody is incubated overnight.Western blots of cell lysates are performed using Goat anti-Rabbit IgG Heavy and Light Chain Antibody (Cat. No. A120-101P).

All western blot analysis is performed using 5% Milk-TBST for blocking and as antibody diluent. Primary antibody is incubated overnight.

Western blots of cell lysates are performed using Goat anti-Rabbit IgG Heavy and Light Chain Antibody (Cat. No. A120-101P).