NEW!
Rabbit anti-MIB2/Skeletrophin Antibody Affinity Purified
Bethyl Laboratories
Catalog #
Validated
Target:
MIB2/Skeletrophin
Reactivity:
Human
Applications:
WB
Host:
Rabbit
Clonality:
Polyclonal
Format:
Whole IgG
Immunogen:
between 925 and 975
Isotype:
IgG
Conjugate:
Unconjugated
Purity:
Antigen Affinity Purified
100 µl (1000 µg/ml)
10 µl (1000 µg/ml)
Product Details
Specifications
Verified Reactivity
Human
Antigen Species
Human
Concentration
1000 µg/ml
Storage
2 - 8 °C
Shelf Life
1 year from date of receipt
Physical State
Liquid
Buffer
Additional Product Information
MIB2/Skeletrophin is an actin-binding protein that bears two MIB/HERC2 domains, a ZZ-type zinc-finger domain, nine ankyrin repeats, and two RING-finger domains. The C-terminal RING domain has been found to have E3 ubiquitin ligase activity that mediates ubiquitination of the intracellular regions of the Notch receptor and its ligands to regulate Notch signaling. MIB2/Skeletrophin appears to be important to muscle development and may function as a suppressor of melanoma invasion.
Alternate Names
E3 ubiquitin-protein ligase MIB2; mind bomb homolog 2; mindbomb homolog 2; novel zinc finger protein; novelzin; putative NF-kappa-B-activating protein 002N; RING-type E3 ubiquitin transferase MIB2; skeletrophin; zinc finger ZZ type with ankyrin repeat domain protein 1; zinc finger, ZZ type with ankyrin repeat domain 1; ZZANK1; ZZZ5
Applications
