Rabbit anti-KCNMA1 Antibody
Catalog #
KCNMA1
Human
IP
,WB
Rabbit
Polyclonal
Whole IgG
between 450 and 500
IgG
Unconjugated
Antigen Affinity Purified
Product Details
Human
Mouse,
Dog,
Chicken,
Pig,
Rabbit,
X_laevis,
Bovine,
Monkey,
Rat
Human
2 - 8 °C
1 year from date of receipt
KCNMA1 (potassium large conductance calcium-activated channel, subfamily M, alpha member 1) is a potassium channel activated by both membrane depolarization or increase in cytosolic Ca2+ that mediates export of K+. KCNMA1 is also activated by the concentration of cytosolic Mg2+. Its activation dampens the excitatory events that elevate the cytosolic Ca2+ concentration and/or depolarize the cell membrane. KCNMA1 therefore contributes to repolarization of the membrane potential, and plays a key role in controlling excitability in a number of systems, such as regulation of the contraction of smooth muscle, the tuning of hair cells in the cochlea, regulation of transmitter release, and innate immunity.1, maxi K channel, MaxiK, Slo-alpha, slo1, slowpoke homolog, Slo homolog, and hSlo [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q12791].
Calcium-activated potassium channel subunit alpha-1
Alternate Names
bA205K10.1; big potassium channel alpha subunit; BK channel; BK channel alpha subunit; BKCA alpha; BKCA alpha subunit; BKTM; CADEDS; calcium-activated potassium channel subunit alpha-1; calcium-activated potassium channel, subfamily M subunit alpha-1; hSlo; k(VCA)alpha; KCa1.1; Maxi K channel; MaxiK; maxi-K channel HSLO; mSLO1; PNKD3; potassium channel, calcium activated large conductance subfamily M alpha, member 1; potassium large conductance calcium-activated channel, subfamily M, alpha member 1; SAKCA; SLO; slo homolog; SLO1; SLO-ALPHA; slowpoke homolog; stretch-activated Kca channel; uncharacterized protein
Applications