/ ANTIBODIES/ANTISERA / Primary Antibodies / Rabbit anti-INT1 Antibody
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Primary Antibodies  

Rabbit anti-INT1 Antibody

Bethyl Laboratories®
Bethyl Laboratories®

Catalog #

Validated
Citations (14)
Target:

INT1

Reactivity:

Human

,

Mouse

Applications:

IP

,

WB

Host:

Rabbit

Clonality:

Polyclonal

Format:

Whole IgG

Immunogen:

between 150 and 200

Isotype:

IgG

Conjugate:

Unconjugated

Purity:

Antigen Affinity Purified

100 µl (1000 µg/ml)

10 µl (1000 µg/ml)

Product Details

Specifications
Verified Reactivity

Mouse,

Human

Antigen Species

Human

Concentration
1000 µg/ml
Storage

2 - 8 °C

Shelf Life

1 year from date of receipt

Physical State
Liquid
Buffer

Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% Sodium Azide


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Additional Product Information

INT1 was first identified as KIAA1440, a hypothetical protein predicted from the in silico analysis of long cDNAs isolated in the Kazusa cDNA sequencing project. Targeted disruption of INT1 results in growth arrest at the early blastocyst stage, activated caspase-3/7 that results in apoptosis, and impaired processing of U2 snRNA. INT1 has been demonstrated to be the largest subunit of the integrator complex which functions to mediate U1 and U2 snRNA 3’end processing.

26173

INTS1

integrator complex subunit 1

Q8N201

Integrator complex subunit 1

Alternate Names

INT1; integrator complex subunit 1; NET28

Applications

All western blot analysis is performed using 5% Milk-TBST for blocking and as antibody diluent. Primary antibody is incubated overnight.

Western blots of cell lysates are performed using Goat anti-Rabbit IgG Heavy and Light Chain Antibody (Cat. No. A120-101P).

Western blots of immunoprecipitates are performed using Goat anti-Rabbit Light Chain HRP Conjugate (Cat. No. A120-113P) with 5% Normal Pig Serum (Cat. No. S100-020) added to the blocking buffer.