Rabbit anti-hPrp3p Antibody Affinity Purified
Catalog #
hPrp3p
Human
IP
Rabbit
Polyclonal
Whole IgG
between 150 and 200
IgG
Unconjugated
Antigen Affinity Purified
Product Details
Human
Mouse,
Bovine
Human
2 - 8 °C
1 year from date of receipt
hPrp3p (human pre-mRNA splicing factor 3) was identified as a factor that associated with U4/U6 snRNPs which are components of the splicesome. hPrp3p is homologous to S. cerevisiae splicing factor Prp3p. Mutations in the PRPF3 gene are associated with retinitis pigmentosa-18. It has been determined that mutations in hPrp3p may alter the recognition motif for phosphorylation by casein kinase II (CKII) and that loss of phosphorylation may result in aberrant interactions within the U4/U6 snRNP complex.
Alternate Names
HPRP3; HPRP3P; pre-mRNA-splicing factor 3; PRP3; PRP3 pre-mRNA processing factor 3 homolog; Prp3p; RP18; SNRNP90; U4/U6 small nuclear ribonucleoprotein Prp3; U4/U6 snRNP 90 kDa protein; U4/U6-associated RNA splicing factor
Applications